| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 |
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| Ligand | BDBM119072 |
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| Substrate/Competitor | n/a |
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| IC50 | 1.204e+4±n/a nM |
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| Citation |  Hrast, M; Sosic, I; Sink, R; Gobec, S Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F. Bioorg Chem55:2-15 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 |
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| Name: | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 |
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| Synonyms: | MURA2_STAAM | MurA (S. aureus) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | murA2 | murZ |
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| Type: | Protein |
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| Mol. Mass.: | 45068.88 |
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| Organism: | Staphylococcus aureus (Firmicutes) |
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| Description: | S. aureus MurA |
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| Residue: | 419 |
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| Sequence: | MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLE
DLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPL
GPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYAT
GQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGT
YMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLV
YPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPST
LHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
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| BDBM119072 |
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| n/a |
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| Name | BDBM119072 |
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| Synonyms: | MurA inhibitor (compound 8) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O |
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| Mol. Mass. | 244.3321 |
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| SMILES | CN1CCN(CC1)C1CCc2ccccc2C1=O |
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| Structure | 
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