| Reaction Details |
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 | Report a problem with these data |
| Target | DNA primase |
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| Ligand | BDBM50366826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Quatitative Inhibition Analysis Assay |
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| pH | 8.8±n/a |
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| IC50 | 7.5e+4± 1.0e+4 nM |
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| Comments | extracted |
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| Citation |  Biswas, T; Green, KD; Garneau-Tsodikova, S; Tsodikov, OV Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry52:6905-10 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA primase |
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| Name: | DNA primase |
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| Synonyms: | DNA primase (Ba DnaG) |
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| Type: | Protein |
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| Mol. Mass.: | 68258.37 |
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| Organism: | Bacillus anthracis (Firmicutes) |
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| Description: | A0A6L8PXB3 |
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| Residue: | 598 |
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| Sequence: | MGNRIPEEVVEQIRTSSDIVEVIGEYVQLRKQGRNYFGLCPFHGENSPSFSVSSDKQIFH
CFGCGEGGNVFSFLMKMEGLAFTEAVQKLGERNGIAVAEYTSGQGQQEDISDDTVIMQQA
HELLKKYYHHLLVNTEEGNEALSYLLKRGITKEMIEKFEIGYASPAWDAATKILQKRGLS
LSSMEQAGLLIRSEKDGSHYDRFRGRVMFPIYTLQGKVIAFSGRALGDDTPKYLNSPETP
IFHKSKLLYNFHQARPFIRKRGQVVLFEGYADVLAAVKSGVEEAVATMGTALTEEQAKLL
RRNVETVVLCYDGDKAGREATMKAGQLLLQVGCQVKVTSLPDKLDPDEYVQQYGTTAFEN
LVKSSISFVGFKINYLRLGKNLQDESGKEEYVKSVLKELSLLQDAMQAESYLKSLSQEFS
YSMETLLNQLHQYRKEQKVQQKQVKQVSKPSQIVQTKPKLTGFERAEREIIYHMLQSPEV
AVRMESHIEDFHTEEHKGILYELYAYYEKGNEPSVGTFLSWLSDEKLKNIITDISTDEFI
NPEYTEEVLQSHLETLRRHQEKLEKMEIIFKIKQMEKTDPVEAAKYYVAYLQNQKARK
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| BDBM50366826 |
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| n/a |
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| Name | BDBM50366826 |
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| Synonyms: | DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaquin |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20FN3O4 |
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| Mol. Mass. | 361.3675 |
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| SMILES | C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |r| |
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| Structure | 
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