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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Hormone-sensitive lipase | ||
| Ligand | BDBM120376 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| pH | 7.2±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 37±n/a nM | ||
| Comments | extracted | ||
| Citation |  Hunziker, D; Neidhart, W Azaspirodecanone compounds US Patent US8703807 Publication Date 4/22/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Hormone-sensitive lipase | |||
| Name: | Hormone-sensitive lipase | ||
| Synonyms: | HSL | Hormone sensitive lipase | Hormone-sensitive lipase (HSL) | LIPE | LIPS_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 116599.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q05469 | ||
| Residue: | 1076 | ||
| Sequence: |
| ||
| BDBM120376 | |||
| n/a | |||
| Name | BDBM120376 | ||
| Synonyms: | US8703807, 12 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H30FNO4 | ||
| Mol. Mass. | 379.4656 | ||
| SMILES | CC(C)Oc1ccc(cc1)N1CC[C@]2(CC[C@@](O)(COCCF)CC2)C1=O |r,wU:16.17,wD:13.13,16.18,(10.08,.62,;8.59,.22,;8.19,-1.27,;7.5,1.31,;6.01,.91,;5.61,-.58,;4.13,-.98,;3.04,.11,;3.44,1.6,;4.92,2,;1.55,-.29,;1.07,-1.75,;-.47,-1.75,;-.94,-.29,;-1.34,1.2,;-2.83,1.6,;-3.92,.51,;-4.69,1.84,;-5.46,.51,;-6.23,-.82,;-7.77,-.82,;-8.54,-2.16,;-10.08,-2.16,;-3.52,-.98,;-2.03,-1.38,;.3,.62,;.3,2.16,)| | ||
| Structure | 
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