| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin receptor type 2 |
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| Ligand | BDBM123330 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay I |
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| pH | 7.5±n/a |
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| Temperature | 277.15±n/a K |
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| Kd | 121±n/a nM |
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| Comments | extracted |
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| Citation |  Badiger, S; Behnke, D; Betschart, C; Chaudhari, V; Chebrolu, M; Cotesta, S; Hintermann, S; Meyer, A; Pandit, C Disubstituted heteroaryl-fused pyridines US Patent US8742106 Publication Date 6/3/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Orexin receptor type 2 |
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| Name: | Orexin receptor type 2 |
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| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R |
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| Type: | Protein |
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| Mol. Mass.: | 50710.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43614 |
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| Residue: | 444 |
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| Sequence: | MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
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| BDBM123330 |
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| n/a |
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| Name | BDBM123330 |
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| Synonyms: | US8742106, 1.17 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21F3N4O2 |
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| Mol. Mass. | 454.4443 |
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| SMILES | C[C@H](NC(=O)COc1cc(c2c(nn(C)c2n1)-c1ccccc1)C(F)(F)F)c1ccccc1 |r| |
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| Structure | 
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