| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
|---|
| Ligand | BDBM125959 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Scintillation Proximity Assay |
|---|
| pH | 7.5±n/a |
|---|
| IC50 | 20±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  De Lombaert, S; Liu, W; Lo, HY; Nemoto, PA Benzimidazole inhibitors of leukotriene production US Patent US8772304 Publication Date 7/8/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arachidonate 5-lipoxygenase-activating protein |
|---|
| Name: | Arachidonate 5-lipoxygenase-activating protein |
|---|
| Synonyms: | 5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 18159.90 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P20292 |
|---|
| Residue: | 161 |
|---|
| Sequence: | MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
|
|
|
|---|
| BDBM125959 |
|---|
| n/a |
|---|
| Name | BDBM125959 |
|---|
| Synonyms: | US8772304, 21 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H20FN9 |
|---|
| Mol. Mass. | 429.4529 |
|---|
| SMILES | CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1cc(F)cnc1-n1cncn1 |
|---|
| Structure | 
|
|---|
Search and Browse
