| Reaction Details |
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 | Report a problem with these data |
| Target | Epoxide hydrolase 1 |
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| Ligand | BDBM50383476 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Activity Assay |
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| IC50 | 50±n/a nM |
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| Citation |  Hammock, BD; Zheng, J; Morisseau, C; Motoba, K; Moghaddam, MF; Borhan, B; Grant, DF; Greene, J; Sisemore, MF; Sanborn, J Inhibitors of epoxide hydrolases for the treatment of inflammation US Patent US8815951 Publication Date 8/26/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Epoxide hydrolase 1 |
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| Name: | Epoxide hydrolase 1 |
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| Synonyms: | Ephx1 | Epoxide hydrolase (HsEH) | Epoxide hydrolase (MsEH) | HYEP_MOUSE |
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| Type: | Protein |
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| Mol. Mass.: | 52586.43 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q9D379 |
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| Residue: | 455 |
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| Sequence: | MWLELILASVLGFVIYWFVSRDKEETLPLEDGWWGPGSKPSAKEDESIRPFKVETSDEEI
KDLHQRIDRFRASPPLEGSRFHYGFNSSYLKKVVSFWRNEFDWRKQVEILNQYPHFKTKI
EGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKTHGLSDEHVFEV
ICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQKFYIQGGDWGSLICTNIAQMVP
NHVKGLHLNMSFISRNIYSLTPLLGQRFGRFLGYTEKDLELLYPFKEKVFYNIMRESGYL
HIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLEDLLTNIMI
YWTTGTIVSSQRFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVKVKYPKL
ISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ
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| BDBM50383476 |
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| n/a |
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| Name | BDBM50383476 |
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| Synonyms: | CHEMBL2031923 | US8815951, 438 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28N2O |
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| Mol. Mass. | 312.4491 |
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| SMILES | O=C(NCCCc1ccccc1)NC12CC3CC(CC(C3)C1)C2 |TLB:12:13:16:20.19.18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13| |
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| Structure | 
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