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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102510 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 530±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102510 | |||
| n/a | |||
| Name | BDBM102510 | ||
| Synonyms: | US8536175, 24 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H16Cl2N4O4 | ||
| Mol. Mass. | 471.293 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(=O)[nH]c2)c2nccnc12 |(6.55,4,;7.32,2.67,;6.55,1.33,;7.31,,;6.55,-1.33,;7.32,-2.67,;8.86,-2.67,;5.01,-1.33,;4.23,-2.67,;4.23,,;5.01,1.33,;4.23,2.67,;2.69,,;1.93,1.33,;.38,1.33,;-.38,,;-1.92,,;-2.69,1.33,;-2.69,-1.33,;-4.23,-1.33,;-5,,;-6.54,,;-7.31,-1.33,;-8.85,-1.33,;-6.54,-2.67,;-5,-2.67,;.38,-1.33,;-.38,-2.67,;.38,-4,;1.93,-4,;2.69,-2.67,;1.93,-1.33,)| | ||
| Structure | 
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