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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102514 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 270±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102514 | |||
| n/a | |||
| Name | BDBM102514 | ||
| Synonyms: | US8536175, 38 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H28Cl2N6O3 | ||
| Mol. Mass. | 555.456 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(nc2)N(C)CCN(C)C)c2nccnc12 |(11.17,2.67,;9.63,2.67,;8.86,1.33,;9.63,,;8.86,-1.33,;9.63,-2.67,;11.17,-2.67,;7.31,-1.33,;6.55,-2.67,;6.55,,;7.31,1.33,;6.55,2.67,;5.01,,;4.24,1.33,;2.7,1.33,;1.92,,;.39,,;-.39,1.33,;-.39,-1.33,;-1.92,-1.33,;-2.7,,;-4.24,,;-5.01,-1.33,;-4.24,-2.67,;-2.7,-2.67,;-6.55,-1.33,;-7.32,-2.67,;-7.32,,;-8.86,,;-9.63,-1.33,;-8.86,-2.67,;-11.17,-1.33,;2.7,-1.33,;1.92,-2.67,;2.7,-4,;4.24,-4,;5.01,-2.67,;4.24,-1.33,)| | ||
| Structure | 
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