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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102520 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | >10000±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102520 | |||
| n/a | |||
| Name | BDBM102520 | ||
| Synonyms: | US8536175, 115 | US8815901, 77 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H29N7O | ||
| Mol. Mass. | 455.5548 | ||
| SMILES | CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4c(C)cccc4C)c4nccnc34)[nH]2)CC1 |(-10.29,.87,;-8.96,.1,;-7.63,.87,;-6.29,.1,;-6.29,-1.44,;-4.96,-2.21,;-3.63,-1.44,;-3.63,.1,;-2.16,.58,;-1.26,-.67,;.28,-.67,;1.05,.67,;.28,2,;2.59,.67,;3.36,2,;4.9,2,;5.67,.67,;7.21,.67,;7.98,2,;7.21,3.33,;9.52,2,;10.29,.67,;9.52,-.67,;7.98,-.67,;7.21,-2,;4.9,-.67,;5.67,-2,;4.9,-3.33,;3.36,-3.33,;2.59,-2,;3.36,-.67,;-2.16,-1.91,;-7.63,-2.21,;-8.96,-1.44,)| | ||
| Structure | 
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