Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102525 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 485±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102525 | |||
| n/a | |||
| Name | BDBM102525 | ||
| Synonyms: | US8536175, 91 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H16F2N4O3 | ||
| Mol. Mass. | 422.3842 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccccn2)c2nccnc12 |(8.09,-2.67,;6.55,-2.67,;5.78,-1.33,;6.55,,;5.78,1.33,;6.55,2.67,;5.78,4,;4.23,1.33,;3.47,2.67,;3.47,,;4.23,-1.33,;3.47,-2.67,;1.93,,;1.15,1.33,;-.38,1.33,;-1.15,,;-2.69,,;-3.47,1.33,;-3.47,-1.33,;-5,-1.33,;-5.78,,;-7.31,,;-8.08,-1.33,;-7.31,-2.67,;-5.78,-2.67,;-.38,-1.33,;-1.15,-2.67,;-.38,-4,;1.15,-4,;1.93,-2.67,;1.15,-1.33,)| | ||
| Structure | 
| ||