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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM130075 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 7±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM130075 | |||
| n/a | |||
| Name | BDBM130075 | ||
| Synonyms: | US8815901, 93 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H24F2N6O3 | ||
| Mol. Mass. | 494.4933 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ncc(CN3CCCC3)[nH]2)c2nccnc12 |(10.31,-2.67,;8.77,-2.67,;8,-1.33,;8.77,,;8,1.33,;8.77,2.67,;8,4,;6.46,1.33,;5.69,2.67,;5.69,,;6.46,-1.33,;5.69,-2.67,;4.15,,;3.38,1.33,;1.84,1.33,;1.07,,;-.47,,;-1.24,1.33,;-1.24,-1.33,;-2.78,-1.33,;-3.69,-.09,;-5.15,-.56,;-5.15,-2.1,;-6.48,-2.87,;-7.82,-2.1,;-8.29,-.64,;-9.83,-.64,;-10.31,-2.1,;-9.06,-3.01,;-3.69,-2.58,;1.84,-1.33,;1.07,-2.67,;1.84,-4,;3.38,-4,;4.15,-2.67,;3.38,-1.33,)| | ||
| Structure | 
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