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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102537 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 11±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102537 | |||
| n/a | |||
| Name | BDBM102537 | ||
| Synonyms: | US8536175, 136 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H24F2N6O4 | ||
| Mol. Mass. | 522.5034 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ccc(CN(C)CC(N)=O)cn2)c2nccnc12 |(11.15,2.66,;9.61,2.66,;8.84,1.32,;9.61,-.01,;8.84,-1.34,;9.61,-2.68,;11.15,-2.68,;7.3,-1.34,;6.53,-2.68,;6.53,-.01,;7.3,1.32,;6.53,2.66,;4.99,-.01,;4.22,1.32,;2.68,1.32,;1.91,-.01,;.37,-.01,;-.4,1.32,;-.4,-1.34,;-1.94,-1.34,;-2.71,-.01,;-4.25,-.01,;-5.02,-1.34,;-6.56,-1.34,;-7.33,-.01,;-6.56,1.32,;-8.87,-.01,;-9.64,1.32,;-8.87,2.66,;-11.18,1.32,;-4.25,-2.68,;-2.71,-2.68,;2.68,-1.34,;1.91,-2.68,;2.68,-4.01,;4.22,-4.01,;4.99,-2.68,;4.22,-1.34,)| | ||
| Structure | 
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