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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM130079 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 11±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM130079 | |||
| n/a | |||
| Name | BDBM130079 | ||
| Synonyms: | US8815901, 153 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H22ClFN6O3 | ||
| Mol. Mass. | 484.911 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2nccnc12 |(7.37,3.96,;8.14,2.62,;7.37,1.29,;8.14,-.04,;7.37,-1.38,;8.14,-2.71,;9.68,-2.71,;5.83,-1.38,;5.06,-2.71,;5.06,-.04,;5.83,1.29,;5.06,2.62,;3.52,-.04,;2.75,1.29,;1.21,1.29,;.44,-.04,;-1.1,-.04,;-1.87,1.29,;-1.87,-1.38,;-3.41,-1.38,;-4.32,-.13,;-5.78,-.61,;-5.78,-2.15,;-7.11,-2.92,;-8.45,-2.15,;-9.78,-2.92,;-8.45,-.61,;-4.32,-2.62,;1.21,-1.38,;.44,-2.71,;1.21,-4.05,;2.75,-4.05,;3.52,-2.71,;2.75,-1.38,)| | ||
| Structure | 
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