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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102547 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 245±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102547 | |||
| n/a | |||
| Name | BDBM102547 | ||
| Synonyms: | US8536175, 173 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H31Cl2N5O3 | ||
| Mol. Mass. | 568.494 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(CN(C)CCN(C)C)cn2)c2ncccc12 |(11.55,2.66,;10.01,2.66,;9.24,1.33,;10.01,-0,;9.24,-1.34,;10.01,-2.67,;11.55,-2.67,;7.7,-1.34,;6.93,-2.67,;6.93,-0,;7.7,1.33,;6.93,2.66,;5.39,-0,;4.62,1.33,;3.08,1.33,;2.31,-0,;.77,-0,;-0,1.33,;-0,-1.34,;-1.54,-1.34,;-2.31,-0,;-3.85,-0,;-4.62,-1.34,;-6.16,-1.34,;-6.93,-0,;-6.16,1.33,;-8.47,-0,;-9.24,-1.34,;-10.78,-1.34,;-11.55,-2.67,;-11.55,-0,;-3.85,-2.67,;-2.31,-2.67,;3.08,-1.34,;2.31,-2.67,;3.08,-4.01,;4.62,-4.01,;5.39,-2.67,;4.62,-1.34,)| | ||
| Structure | 
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