| Reaction Details |
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 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
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| Ligand | BDBM130685 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay |
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| Temperature | 280.65±n/a K |
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| IC50 | 1.5±n/a nM |
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| Citation |  Chen, Z; De Lombaert, S; Dines, JA; Liu, W; Lo, HY; Loke, PL Benzimidazole inhibitors of leukotriene production US Patent US8829200 Publication Date 9/9/2014 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Arachidonate 5-lipoxygenase-activating protein |
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| Name: | Arachidonate 5-lipoxygenase-activating protein |
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| Synonyms: | 5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 18159.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20292 |
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| Residue: | 161 |
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| Sequence: | MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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| BDBM130685 |
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| n/a |
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| Name | BDBM130685 |
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| Synonyms: | US8829200, 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25N7O |
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| Mol. Mass. | 463.5337 |
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| SMILES | CC(C)(C)n1c(nc2cc(ccc12)-c1cnc(N)nc1)-c1ccccc1C(=O)Nc1cccnc1 |
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| Structure | 
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