| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase G |
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| Ligand | BDBM139995 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| pH | 7.8±n/a |
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| Temperature | 293.15±n/a K |
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| IC50 | 16800±n/a nM |
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| Comments | extracted |
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| Citation |  Guichou, J; Colliandre, L; Ahmed-Belkacem, H; Pawlotsky, J Inhibitors of cyclophilins and uses thereof US Patent US8901295 Publication Date 12/2/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase G |
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| Name: | Peptidyl-prolyl cis-trans isomerase G |
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| Synonyms: | Cyclophilin A (CYPA) | PPIG | PPIG_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 88718.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13427 |
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| Residue: | 754 |
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| Sequence: | MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHY
KSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGKDTN
GSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGELIPK
SKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRK
HKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK
NRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPP
HWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKN
EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN
EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR
RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRR
RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSES
EKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEK
ENQKSKGQENDHVHEKNKKFDHESSPGTDEDKSG
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| BDBM139995 |
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| n/a |
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| Name | BDBM139995 |
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| Synonyms: | US8901295, F428 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H17N3O3 |
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| Mol. Mass. | 251.2817 |
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| SMILES | CCOC(=O)CNC(=O)NCc1ccc(N)cc1 |
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| Structure | 
|
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