Compile Data Set for Download or QSAR

Found 202 hits with Last Name = 'colliandre' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50243145 (CHEMBL3109141) Show SMILES OCc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-1-4-20(15-17)28-25(33)27-19-8-6-18(7-9-19)23-29-21-5-2-10-26-22(21)24(30-23)31-11-13-34-14-12-31/h1-10,15,32H,11-14,16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495494 (CHEMBL3109116) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)16-19-14-5-2-6-18-15(14)17(20-16)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50243143 (CHEMBL3109142) Show SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-7-19(8-4-17)27-25(33)28-20-9-5-18(6-10-20)23-29-21-2-1-11-26-22(21)24(30-23)31-12-14-34-15-13-31/h1-11,32H,12-16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495487 (CHEMBL3109134) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)13-20-11-2-1-3-17-12(11)14(21-13)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495499 (CHEMBL3109140) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C19H20N6O2/c1-20-19(26)22-14-6-4-13(5-7-14)17-23-15-3-2-8-21-16(15)18(24-17)25-9-11-27-12-10-25/h2-8H,9-12H2,1H3,(H2,20,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50243143 (CHEMBL3109142) Show SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-7-19(8-4-17)27-25(33)28-20-9-5-18(6-10-20)23-29-21-2-1-11-26-22(21)24(30-23)31-12-14-34-15-13-31/h1-11,32H,12-16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495491 (CHEMBL3109139) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)12-20-13-11(2-1-3-17-13)14(21-12)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495494 (CHEMBL3109116) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)16-19-14-5-2-6-18-15(14)17(20-16)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50243143 (CHEMBL3109142) Show SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-7-19(8-4-17)27-25(33)28-20-9-5-18(6-10-20)23-29-21-2-1-11-26-22(21)24(30-23)31-12-14-34-15-13-31/h1-11,32H,12-16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495487 (CHEMBL3109134) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)13-20-11-2-1-3-17-12(11)14(21-13)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495494 (CHEMBL3109116) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)16-19-14-5-2-6-18-15(14)17(20-16)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495498 (CHEMBL3109146) Show SMILES O=C(Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1)Nc1cccnc1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-3-1-9-24-15-18)26-17-7-5-16(6-8-17)21-28-19-4-2-10-25-20(19)22(29-21)30-11-13-32-14-12-30/h1-10,15H,11-14H2,(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495485 (CHEMBL3109143) Show SMILES Oc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C24H22N6O3/c31-19-4-1-3-18(15-19)27-24(32)26-17-8-6-16(7-9-17)22-28-20-5-2-10-25-21(20)23(29-22)30-11-13-33-14-12-30/h1-10,15,31H,11-14H2,(H2,26,27,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495494 (CHEMBL3109116) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)16-19-14-5-2-6-18-15(14)17(20-16)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50243145 (CHEMBL3109141) Show SMILES OCc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-1-4-20(15-17)28-25(33)27-19-8-6-18(7-9-19)23-29-21-5-2-10-26-22(21)24(30-23)31-11-13-34-14-12-31/h1-10,15,32H,11-14,16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495486 (CHEMBL3109144) Show SMILES Oc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C24H22N6O3/c31-19-9-7-18(8-10-19)27-24(32)26-17-5-3-16(4-6-17)22-28-20-2-1-11-25-21(20)23(29-22)30-12-14-33-15-13-30/h1-11,31H,12-15H2,(H2,26,27,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495498 (CHEMBL3109146) Show SMILES O=C(Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1)Nc1cccnc1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-3-1-9-24-15-18)26-17-7-5-16(6-8-17)21-28-19-4-2-10-25-20(19)22(29-21)30-11-13-32-14-12-30/h1-10,15H,11-14H2,(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495486 (CHEMBL3109144) Show SMILES Oc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C24H22N6O3/c31-19-9-7-18(8-10-19)27-24(32)26-17-5-3-16(4-6-17)22-28-20-2-1-11-25-21(20)23(29-22)30-12-14-33-15-13-30/h1-11,31H,12-15H2,(H2,26,27,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50243143 (CHEMBL3109142) Show SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-7-19(8-4-17)27-25(33)28-20-9-5-18(6-10-20)23-29-21-2-1-11-26-22(21)24(30-23)31-12-14-34-15-13-31/h1-11,32H,12-16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495487 (CHEMBL3109134) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)13-20-11-2-1-3-17-12(11)14(21-13)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495497 (CHEMBL3109115) Show SMILES Oc1cccc(c1)-c1nc(nc2cccnc12)N1CCOCC1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)15-16-14(5-2-6-18-16)19-17(20-15)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50355909 (CHEMBL1910195) Show SMILES Oc1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H14N2O2/c22-16-4-1-12(2-5-16)14-7-15(11-20-10-14)18-8-13-3-6-17(23)9-19(13)21-18/h1-11,21-23H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ...				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50243145 (CHEMBL3109141) Show SMILES OCc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-1-4-20(15-17)28-25(33)27-19-8-6-18(7-9-19)23-29-21-5-2-10-26-22(21)24(30-23)31-11-13-34-14-12-31/h1-10,15,32H,11-14,16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495499 (CHEMBL3109140) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C19H20N6O2/c1-20-19(26)22-14-6-4-13(5-7-14)17-23-15-3-2-8-21-16(15)18(24-17)25-9-11-27-12-10-25/h2-8H,9-12H2,1H3,(H2,20,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495498 (CHEMBL3109146) Show SMILES O=C(Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1)Nc1cccnc1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-3-1-9-24-15-18)26-17-7-5-16(6-8-17)21-28-19-4-2-10-25-20(19)22(29-21)30-11-13-32-14-12-30/h1-10,15H,11-14H2,(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495487 (CHEMBL3109134) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)13-20-11-2-1-3-17-12(11)14(21-13)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495499 (CHEMBL3109140) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C19H20N6O2/c1-20-19(26)22-14-6-4-13(5-7-14)17-23-15-3-2-8-21-16(15)18(24-17)25-9-11-27-12-10-25/h2-8H,9-12H2,1H3,(H2,20,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495500 (CHEMBL3109137) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)15-19-16-14(5-2-6-18-16)17(20-15)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50243145 (CHEMBL3109141) Show SMILES OCc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-1-4-20(15-17)28-25(33)27-19-8-6-18(7-9-19)23-29-21-5-2-10-26-22(21)24(30-23)31-11-13-34-14-12-31/h1-10,15,32H,11-14,16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495500 (CHEMBL3109137) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)15-19-16-14(5-2-6-18-16)17(20-15)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495495 (CHEMBL3109138) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)16-20-17-15(5-2-6-19-17)18(21-16)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495498 (CHEMBL3109146) Show SMILES O=C(Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1)Nc1cccnc1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-3-1-9-24-15-18)26-17-7-5-16(6-8-17)21-28-19-4-2-10-25-20(19)22(29-21)30-11-13-32-14-12-30/h1-10,15H,11-14H2,(H2,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495491 (CHEMBL3109139) Show SMILES Nc1ncc(cn1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C15H15N7O/c16-15-18-8-10(9-19-15)12-20-13-11(2-1-3-17-13)14(21-12)22-4-6-23-7-5-22/h1-3,8-9H,4-7H2,(H2,16,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495510 (CHEMBL3109128) Show SMILES Nc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C17H17N5O/c18-13-4-1-3-12(11-13)16-20-14-5-2-6-19-15(14)17(21-16)22-7-9-23-10-8-22/h1-6,11H,7-10,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495507 (CHEMBL3109145) Show SMILES O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-7-10-24-11-8-18)26-17-5-3-16(4-6-17)21-28-19-2-1-9-25-20(19)22(29-21)30-12-14-32-15-13-30/h1-11H,12-15H2,(H2,24,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50355909 (CHEMBL1910195) Show SMILES Oc1ccc(cc1)-c1cncc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H14N2O2/c22-16-4-1-12(2-5-16)14-7-15(11-20-10-14)18-8-13-3-6-17(23)9-19(13)21-18/h1-11,21-23H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [33P-gamma]-ATP after 30 mins by scintillation counting				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495485 (CHEMBL3109143) Show SMILES Oc1cccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)c1 Show InChI InChI=1S/C24H22N6O3/c31-19-4-1-3-18(15-19)27-24(32)26-17-8-6-16(7-9-17)22-28-20-5-2-10-25-21(20)23(29-22)30-11-13-33-14-12-30/h1-10,15,31H,11-14H2,(H2,26,27,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495499 (CHEMBL3109140) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C19H20N6O2/c1-20-19(26)22-14-6-4-13(5-7-14)17-23-15-3-2-8-21-16(15)18(24-17)25-9-11-27-12-10-25/h2-8H,9-12H2,1H3,(H2,20,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50355915 (CHEMBL1910201) Show SMILES Oc1ccc(cc1)-c1ccnc(c1)-c1cc2cc(O)ccc2[nH]1 Show InChI InChI=1S/C19H14N2O2/c22-15-3-1-12(2-4-15)13-7-8-20-18(10-13)19-11-14-9-16(23)5-6-17(14)21-19/h1-11,21-23H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ...				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495486 (CHEMBL3109144) Show SMILES Oc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C24H22N6O3/c31-19-9-7-18(8-10-19)27-24(32)26-17-5-3-16(4-6-17)22-28-20-2-1-11-25-21(20)23(29-22)30-12-14-33-15-13-30/h1-11,31H,12-15H2,(H2,26,27,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495495 (CHEMBL3109138) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2cccnc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)16-20-17-15(5-2-6-19-17)18(21-16)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	268	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50355916 (CHEMBL1910377) Show SMILES Oc1ccc(cc1)-c1ccnc(c1)-c1cc2ccc(O)cc2[nH]1 Show InChI InChI=1S/C19H14N2O2/c22-15-4-1-12(2-5-15)13-7-8-20-18(9-13)19-10-14-3-6-16(23)11-17(14)21-19/h1-11,21-23H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ...				Eur J Med Chem 46: 5416-34 (2011) Article DOI: 10.1016/j.ejmech.2011.08.048 BindingDB Entry DOI: 10.7270/Q2T1542V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495507 (CHEMBL3109145) Show SMILES O=C(Nc1ccncc1)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C23H21N7O2/c31-23(27-18-7-10-24-11-8-18)26-17-5-3-16(4-6-17)21-28-19-2-1-9-25-20(19)22(29-21)30-12-14-32-15-13-30/h1-11H,12-15H2,(H2,24,26,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair

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