| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase D |
|---|
| Ligand | BDBM140002 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| pH | 7.8±n/a |
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| Temperature | 293.15±n/a K |
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| IC50 | 1400±n/a nM |
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| Comments | extracted |
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| Citation |  Guichou, J; Colliandre, L; Ahmed-Belkacem, H; Pawlotsky, J Inhibitors of cyclophilins and uses thereof US Patent US8901295 Publication Date 12/2/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Peptidyl-prolyl cis-trans isomerase D |
|---|
| Name: | Peptidyl-prolyl cis-trans isomerase D |
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| Synonyms: | 40 kDa peptidyl-prolyl cis-trans isomerase | CYP-40 | CYP40 | CYPD | Cyclophilin D (CypD) | Cyclophilin-40 | Cyclophilin-related protein | PPID | PPID_HUMAN | PPIase D | Peptidyl-prolyl cis-trans isomerase D | Rotamase D |
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| Type: | Protein |
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| Mol. Mass.: | 40766.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q08752 |
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| Residue: | 370 |
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| Sequence: | MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGH
TTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSM
ANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAE
CGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWE
MAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEAL
ELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDK
EKAVYAKMFA
|
|
|
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| BDBM140002 |
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| n/a |
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| Name | BDBM140002 |
|---|
| Synonyms: | US8901295, F671 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C24H26N4O2 |
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| Mol. Mass. | 402.4888 |
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| SMILES | Nc1ccc(CNC(=O)NCC(=O)N2CCCC2c2cccc3ccccc23)cc1 |
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| Structure | 
|
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