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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | ||
| Ligand | BDBM140099 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.5±n/a | ||
| Temperature | 277.15±n/a K | ||
| IC50 | 6.5±n/a nM | ||
| Comments | extracted | ||
| Citation |  Inoue, H; Murafuji, H; Hayashi, Y Thienopyrazole derivative having PDE7 inhibitory activity US Patent US8901315 Publication Date 12/2/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | |||
| Name: | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | ||
| Synonyms: | 3',5'-cyclic phosphodiesterase | PDE7A | PDE7A_HUMAN | Phosphodiesterase 7 | Phosphodiesterase 7 (PDE7) | Phosphodiesterase 7A | Phosphodiesterase 7A (PDE7A1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 55514.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13946 | ||
| Residue: | 482 | ||
| Sequence: |
| ||
| BDBM140099 | |||
| n/a | |||
| Name | BDBM140099 | ||
| Synonyms: | US8901315, 188 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H35N5OS | ||
| Mol. Mass. | 429.622 | ||
| SMILES | Cc1nn(C2CCCCC2)c2sc(cc12)C(=O)N[C@H]1CC[C@@H](CC1)N1CCNCC1 |r,wU:18.20,wD:21.27,(-7.32,4.1,;-6.55,2.77,;-7.46,1.52,;-6.55,.27,;-6.95,-1.21,;-8.44,-1.61,;-8.83,-3.1,;-7.75,-4.19,;-6.26,-3.79,;-5.86,-2.3,;-5.09,.75,;-3.62,.27,;-2.72,1.52,;-3.62,2.77,;-5.09,2.29,;-1.18,1.52,;-.41,.19,;-.41,2.85,;1.13,2.85,;1.9,4.19,;3.44,4.19,;4.21,2.85,;3.44,1.52,;1.9,1.52,;5.75,2.85,;6.52,1.52,;8.06,1.52,;8.83,2.85,;8.06,4.19,;6.52,4.19,)| | ||
| Structure | 
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