Reaction Details | |||
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Report a problem with these data | |||
Target | Phosphodiesterase | ||
Ligand | BDBM140087 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
pH | 6.5±n/a | ||
Temperature | 277.15±n/a K | ||
IC50 | 1300±n/a nM | ||
Comments | extracted | ||
Citation | Inoue, H; Murafuji, H; Hayashi, Y Thienopyrazole derivative having PDE7 inhibitory activity US Patent US8901315 Publication Date 12/2/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Phosphodiesterase | |||
Name: | Phosphodiesterase | ||
Synonyms: | Phosphodiesterase 4 (PDE4) | ||
Type: | Protein | ||
Mol. Mass.: | 82059.36 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | Q8VBU5 | ||
Residue: | 721 | ||
Sequence: |
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BDBM140087 | |||
n/a | |||
Name | BDBM140087 | ||
Synonyms: | US8901315, 166 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H37N5OS | ||
Mol. Mass. | 443.648 | ||
SMILES | CN1CCN(CC1)[C@H]1CC[C@@H](CC1)NC(=O)c1cc2c(C)nn(C3CCCCC3)c2s1 |r,wU:10.14,wD:7.7,(9.6,2.85,;8.06,2.85,;7.29,1.52,;5.75,1.52,;4.98,2.85,;5.75,4.19,;7.29,4.19,;3.44,2.85,;2.67,4.19,;1.13,4.19,;.36,2.85,;1.13,1.52,;2.67,1.52,;-1.18,2.85,;-1.95,1.52,;-1.18,.19,;-3.49,1.52,;-4.39,2.77,;-5.86,2.29,;-7.32,2.77,;-8.09,4.1,;-8.23,1.52,;-7.32,.27,;-7.72,-1.21,;-9.21,-1.61,;-9.6,-3.1,;-8.52,-4.19,;-7.03,-3.79,;-6.63,-2.3,;-5.86,.75,;-4.39,.27,)| | ||
Structure |