| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Ligand | BDBM144270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Competition Binding Assay |
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| Ki | 8.56±n/a nM |
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| Citation |  Omoto, K; Owen, RM; Pryde, DC; Watson, CA; Takeuchi, M Chemical compounds US Patent US8952008 Publication Date 2/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-2 |
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| Synonyms: | GABA receptor alpha-2 subunit | GABRA2 | GBRA2_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2) |
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| Type: | Protein |
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| Mol. Mass.: | 51338.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47869 |
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| Residue: | 451 |
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| Sequence: | MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
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| BDBM144270 |
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| n/a |
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| Name | BDBM144270 |
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| Synonyms: | US8952008, 38 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21FN4O3S |
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| Mol. Mass. | 440.491 |
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| SMILES | COc1cc(ccc1-c1cc(ccc1F)-c1cnnc2n(cnc12)C(C)C)S(C)(=O)=O |
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| Structure | 
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