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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium channel protein type 9 subunit alpha | ||
| Ligand | BDBM145624 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Radioligand Binding Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 3±n/a nM | ||
| Comments | extracted | ||
| Citation |  Andrez, J; Chowdhury, S; Decker, SM; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Li, J; Ortwine, DF; Safina, B; Sheng, T; Sun, S; Sutherlin, DP; Wilson, MS; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US8952169 Publication Date 2/10/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium channel protein type 9 subunit alpha | |||
| Name: | Sodium channel protein type 9 subunit alpha | ||
| Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
| Type: | Protein | ||
| Mol. Mass.: | 226375.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15858 | ||
| Residue: | 1988 | ||
| Sequence: |
| ||
| BDBM145624 | |||
| n/a | |||
| Name | BDBM145624 | ||
| Synonyms: | US8952169, 427 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H28F4N2O4S | ||
| Mol. Mass. | 492.527 | ||
| SMILES | CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(=O)(=O)N2CCC2)CCC(CC1)C(F)(F)F |(-4.28,-.69,;-4.28,.85,;-2.94,.08,;-1.61,.85,;-.28,.08,;1.06,.85,;2.39,.08,;3.72,.85,;2.39,-1.46,;1.06,-2.23,;-.28,-1.46,;-1.61,-2.23,;-3.15,-2.23,;-2.38,-3.57,;3.72,-2.23,;3.72,-3.77,;5.06,-1.46,;6.39,-2.23,;5.62,-3.57,;7.16,-.9,;7.73,-3,;8.12,-4.49,;9.61,-4.09,;9.21,-2.6,;-4.28,2.39,;-5.61,3.16,;-6.94,2.39,;-6.94,.85,;-5.61,.08,;-8.28,3.16,;-9.61,3.93,;-7.51,4.49,;-9.05,1.82,)| | ||
| Structure | 
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