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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium channel protein type 9 subunit alpha | ||
| Ligand | BDBM145276 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Electrophysiological Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 3.1±n/a nM | ||
| Comments | extracted | ||
| Citation |  Andrez, J; Chowdhury, S; Decker, SM; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Li, J; Ortwine, DF; Safina, B; Sheng, T; Sun, S; Sutherlin, DP; Wilson, MS; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US8952169 Publication Date 2/10/2015 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium channel protein type 9 subunit alpha | |||
| Name: | Sodium channel protein type 9 subunit alpha | ||
| Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
| Type: | Protein | ||
| Mol. Mass.: | 226375.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15858 | ||
| Residue: | 1988 | ||
| Sequence: |
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| BDBM145276 | |||
| n/a | |||
| Name | BDBM145276 | ||
| Synonyms: | US8952169, 55 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29NO4S | ||
| Mol. Mass. | 403.535 | ||
| SMILES | CS(=O)(=O)NC(=O)c1ccc(OCC2C3CC4CC(C3)CC2C4)c(c1)C1CC1 |TLB:12:13:15:17.18.19,THB:13:21:17:15.14.19,13:14:17:21.20.22,20:21:15:17.18.19,20:18:15:21.13.22,(7.75,1.73,;6.42,2.5,;5.65,3.84,;7.19,3.84,;5.08,1.73,;3.75,2.5,;3.75,4.04,;2.41,1.73,;1.08,2.5,;-.25,1.73,;-.25,.19,;-1.59,-.58,;-2.92,.19,;-4.25,-.58,;-5.58,.19,;-6.92,-.58,;-6.92,-2.12,;-7.75,-4.02,;-6.35,-3.37,;-6.34,-.97,;-5.15,-4.04,;-4.25,-2.12,;-5.58,-2.89,;1.08,-.58,;2.41,.19,;1.08,-2.12,;.31,-3.45,;1.85,-3.45,)| | ||
| Structure | 
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