| Reaction Details |
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 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
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| Ligand | BDBM145824 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Homogeneous Time Resolved Fluorescence Assay |
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| Ki | 3±n/a nM |
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| Citation |  Chai, W; Dvorak, CA; Eccles, W; Edwards, JP; Goldberg, SD; Krawczuk, PJ; Lebsack, AD; Liu, J; Pippel, DJ; Sales, ZS; Tanis, VM; Tichenor, MS; Wiener, JJ 1,2,6-substituted benzimidazoles as FLAP modulators US Patent US8952177 Publication Date 2/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Arachidonate 5-lipoxygenase-activating protein |
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| Name: | Arachidonate 5-lipoxygenase-activating protein |
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| Synonyms: | 5-lipoxygenase-activating protein (FLAP) | A0A087WW23_HUMAN | ALOX5AP |
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| Type: | Protein |
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| Mol. Mass.: | 24212.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | A0A087WW23 |
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| Residue: | 218 |
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| Sequence: | MLTFNHDAPWHTQKTLKTSEFGKSFGTLGHIGNISHQCWAGCAAGGRAVLSGEPEANMDQ
ETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDA
YPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLF
LMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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| BDBM145824 |
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| n/a |
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| Name | BDBM145824 |
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| Synonyms: | US8952177, 180 | US8952177, 182 | US9089569, 182 | US9695149, 182 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H41FN4O3 |
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| Mol. Mass. | 572.7127 |
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| SMILES | CCC(CC)(Cc1nc2ccc(OCc3ncc(C)cc3F)cc2n1Cc1ccc(cc1)N1CCC(C)CC1)C(O)=O |
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| Structure | 
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