| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM147188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Dose-Displacement Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 323.15±n/a K |
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| Ki | 112.19±n/a nM |
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| Comments | extracted |
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| Citation |  Kyle, DJ; Tafesse, L; Zhou, X 7,8-cyclicmorphinan analogs US Patent US8957084 Publication Date 2/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
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|
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| BDBM147188 |
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| n/a |
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| Name | BDBM147188 |
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| Synonyms: | US8957084, 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO2 |
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| Mol. Mass. | 337.4553 |
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| SMILES | COc1ccc2C[C@@H]3C4C5CC5C(=O)C[C@]4(CCN3CC3CC3)c2c1 |r,w:9.8,TEB:9:8:6.5.23:16.18.17| |
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| Structure | 
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