| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM192470 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cellular In Vitro Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 820±n/a nM |
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| Comments | extracted |
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| Citation |  Fürstner, C; Keldenich, J; Delbeck, M; Kolkhof, P; Kretschmer, A; Pluschkell, I; Pook, E; Schmeck, C; Trübel, H Bisaryl-bonded aryltriazolones and use thereof US Patent US9687476 Publication Date 6/27/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM192470 |
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| n/a |
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| Name | BDBM192470 |
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| Synonyms: | US9187466, 112 | US9687476, 112 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18Cl3N5O |
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| Mol. Mass. | 474.77 |
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| SMILES | Clc1ccc(cc1)-c1nn(Cc2cncn2Cc2c(Cl)cccc2Cl)c(=O)n1CC=C |
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| Structure | 
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