| Reaction Details |
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 | Report a problem with these data |
| Target | Uncharacterized protein |
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| Ligand | BDBM50446171 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescent Kinase Assay |
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| IC50 | 10.00±n/a nM |
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| Citation |  Fan, E; Van Voorhis, WC; Zhang, Z; Huang, W; Ojo, KK 5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum US Patent US9518026 Publication Date 12/13/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Uncharacterized protein |
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| Name: | Uncharacterized protein |
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| Synonyms: | Calmodulin-domain protein kinase (CDPK1) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60946.72 |
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| Organism: | Cryptosporidium parvum |
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| Description: | n/a |
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| Residue: | 538 |
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| Sequence: | MGNTAVGNTGTRLRAPVDAVVNTTNKKAPVSEKPSQPQIPNKTSDVKKGGTMGGERGSVT
TGMFVQSGSGTFAERYNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINKASAKNKDTSTI
LREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIK
QVFSGITYMHKHNIVHRDLKPENILLESKEKDCDIKIIDFGLSTCFQQNTKMKDRIGTAY
YIAPEVLRGTYDEKCDVWSAGVILYILLSGTPPFYGKNEYDILKRVETGKYAFDLPQWRT
ISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQA
EKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDS
NSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDK
DGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQNFVRNE
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| BDBM50446171 |
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| n/a |
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| Name | BDBM50446171 |
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| Synonyms: | CHEMBL3108999 | US9518026, Example 26 | US9956214, Compound 26 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N4O2 |
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| Mol. Mass. | 366.4567 |
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| SMILES | CCCOc1ccc2cc(ccc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C |
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| Structure | 
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