| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM152509 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Acetylcholinesterase Inhibition Assay |
|---|
| pH | 8±n/a |
|---|
| Ki | 2.78±0.0 nM |
|---|
| IC50 | 4.58±0.0 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Öztaskin, N; Çetinkaya, Y; Taslimi, P; Göksu, S; Gülçin, Ä° Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives. Bioorg Chem60:49-57 (2015) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 67792.70 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22303 |
|---|
| Residue: | 614 |
|---|
| Sequence: | MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
|
|
|
|---|
| BDBM152509 |
|---|
| n/a |
|---|
| Name | BDBM152509 |
|---|
| Synonyms: | (4-Bromo-2,5-dihydroxyphenyl)(4-hydroxyphenyl)methanone (22) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H9BrO4 |
|---|
| Mol. Mass. | 309.112 |
|---|
| SMILES | Oc1ccc(cc1)C(=O)c1cc(O)c(Br)cc1O |
|---|
| Structure | 
|
|---|
Search and Browse
