| Reaction Details |
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 | Report a problem with these data |
| Target | Acylase |
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| Ligand | BDBM50067884 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PVdQ Inhibition Assay |
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| pH | 8±n/a |
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| Ki | 5.50e+5± 9.0e+4 nM |
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| Comments | extracted |
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| Citation |  Clevenger, KD; Wu, R; Liu, D; Fast, W n-Alkylboronic acid inhibitors reveal determinants of ligand specificity in the quorum-quenching and siderophore biosynthetic enzyme PvdQ. Biochemistry53:6679-86 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acylase |
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| Name: | Acylase |
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| Synonyms: | N-terminal nucleophile hydrolase (PVdQ) |
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| Type: | Protein |
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| Mol. Mass.: | 84057.56 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | A0A0G5TC92 |
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| Residue: | 762 |
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| Sequence: | MGMRTVLTGLAGMLLGSMMPVQADMPRPTGLAADIRWTAYGVPHIRAKDERGLGYGIGYA
YARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQT
PAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFAD
ALVAAAPPGTEKVALSGEQAFQVAEQRRQRFRLERGSNAIAVGSERSADGKGMLLANPHF
PWNGAMRFYQMHLTIPGRLDVMGASLPGLPVVNIGFSRHLAWTHTVDTSSHFTLYRLALD
PKDPRRYLVDGRSLPLEEKSVAIEVRGADGKLSRVEHKVYQSIYGPLVVWPGKLDWNRSE
AYALRDANLENTRVLQQWYSINQASDVADLRRRVEALQGIPWVNTLAADEQGNALYMNQS
VVPYLKPELIPACAIPQLVAEGLPALQGQDSRCAWSRDPAAAQAGITPAAQLPVLLRRDF
VQNSNDSAWLTNPASPLQGFSPLVSQEKPIGPRARYALSRLQGKQPLEAKTLEEMVTANH
VFSADQVLPDLLRLCRDNQGENSLARACAALAQWDRGANLDSGSGFVYFQRFMQRFAELD
GAWKEPFDAQRPLDTPQGIALDRPQVATQVRQALADAAAEVEKSGIPDGARWGDLQVSTR
GQERIAIPGGDGHFGVYNAIQSVRKGDHLEVVGGTSYIQLVTFPEEGPKARGLLAFSQSS
DPRSPHYRDQTELFSRQQWQTLPFSDRQIDADPQLQRLSIRE
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| BDBM50067884 |
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| n/a |
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| Name | BDBM50067884 |
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| Synonyms: | 1-BUTANE BORONIC ACID | Borinic acid derivative | Butyl boronic acid | Butylboronic acid | CHEMBL31962 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H11BO2 |
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| Mol. Mass. | 101.94 |
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| SMILES | CCCCB(O)O |
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| Structure | 
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