BindingDB PrimarySearch

Found 50 hits with Last Name = 'fast' and Initial = 'w'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50061231 (2-Amino-5-(N'-propyl-guanidino)-pentanoic acid \| C...) Show SMILES CCCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50138983 ((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...) Show SMILES CSC(N)=NCCC[C@H](N)C(O)=O \|r,w:4.4\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50061231 (2-Amino-5-(N'-propyl-guanidino)-pentanoic acid \| C...) Show SMILES CCCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50061230 (1-Acetyl-4-(N'-allyl-guanidino)-butyl-ammonium) Show SMILES CC(=O)C([NH3+])CCCNC(=N)NCC=C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50061232 (2-Amino-5-(N'-prop-2-ynyl-guanidino)-pentanoic aci...) Show SMILES [NH3+]C(CCCNC(=N)NCC#C)C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50061232 (2-Amino-5-(N'-prop-2-ynyl-guanidino)-pentanoic aci...) Show SMILES [NH3+]C(CCCNC(=N)NCC#C)C([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM92901 (ADMA, 3) Show SMILES CN(C)C(N)=NCCC[C@H](N)C(O)=O \|r,w:5.5\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MMDB PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50061232 (2-Amino-5-(N'-prop-2-ynyl-guanidino)-pentanoic aci...) Show SMILES [NH3+]C(CCCNC(=N)NCC#C)C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent \| (S)-5-Acetim...) Show SMILES CC(N)=NCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Acylase (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM152689 (1-Hexylboronic acid (C6-B(OH)2)) Show SMILES CCCCCCB(O)O Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
The University of Texas					Assay Description Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...				Biochemistry 53: 6679-86 (2014) Article DOI: 10.1021/bi501086s BindingDB Entry DOI: 10.7270/Q2M907DK
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50061230 (1-Acetyl-4-(N'-allyl-guanidino)-butyl-ammonium) Show SMILES CC(=O)C([NH3+])CCCNC(=N)NCC=C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50254450 ((S)-2-Amino-5-propionimidoylamino-pentanoic acid \|...) Show SMILES CCC(N)=NCCC[C@H](N)C(O)=O \|r,w:4.4\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50061230 (1-Acetyl-4-(N'-allyl-guanidino)-butyl-ammonium) Show SMILES CC(=O)C([NH3+])CCCNC(=N)NCC=C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50030279 (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid \| C...) Show SMILES CNC(=N)NCCCC(N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50061233 (2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid \| CH...) Show SMILES CCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92904 (nNOS and DDAH inhibitor, 14) Show SMILES CCCCC(N)=NCCC[C@H](N)C(O)=O \|r,w:6.6\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50061231 (2-Amino-5-(N'-propyl-guanidino)-pentanoic acid \| C...) Show SMILES CCCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50061233 (2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid \| CH...) Show SMILES CCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50030279 (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid \| C...) Show SMILES CNC(=N)NCCCC(N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50030279 (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid \| C...) Show SMILES CNC(=N)NCCCC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50061233 (2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid \| CH...) Show SMILES CCNC(=N)NCCCC([NH3+])C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)				J Med Chem 40: 3869-70 (1998) Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT
Northwestern University Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM92904 (nNOS and DDAH inhibitor, 14) Show SMILES CCCCC(N)=NCCC[C@H](N)C(O)=O \|r,w:6.6\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50254450 ((S)-2-Amino-5-propionimidoylamino-pentanoic acid \|...) Show SMILES CCC(N)=NCCC[C@H](N)C(O)=O \|r,w:4.4\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92905 (DDAH Inhibitor, 15) Show SMILES CCCCCC(N)=NCCC[C@H](N)C(O)=O \|r,w:7.7\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Acylase (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM50067884 (1-BUTANE BORONIC ACID \| Borinic acid derivative \| ...) Show SMILES CCCCB(O)O Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	5.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
The University of Texas					Assay Description Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...				Biochemistry 53: 6679-86 (2014) Article DOI: 10.1021/bi501086s BindingDB Entry DOI: 10.7270/Q2M907DK
The University of Texas					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50404858 (CHEMBL351569) Show SMILES CCc1nc2ccccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs...				Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50072297 ((S)-5-Acetimidoylamino-2-amino-pent \| (S)-5-Acetim...) Show SMILES CC(N)=NCCC[C@H](N)C(O)=O \|r,w:3.3\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	9.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM92903 (L-Citrulline, 4) Show SMILES N[C@@H](CCCNC(N)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50421231 (CHEMBL2087646) Show SMILES NCCSc1nc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs...				Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM92905 (DDAH Inhibitor, 15) Show SMILES CCCCCC(N)=NCCC[C@H](N)C(O)=O \|r,w:7.7\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.90E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
Acylase (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM152687 (1-Ethylboronic acid (C2-B(OH)2)) Show SMILES CCB(O)O Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
The University of Texas					Assay Description Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...				Biochemistry 53: 6679-86 (2014) Article DOI: 10.1021/bi501086s BindingDB Entry DOI: 10.7270/Q2M907DK
The University of Texas					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92903 (L-Citrulline, 4) Show SMILES N[C@@H](CCCNC(N)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	3.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair				3D Structure (crystal)
Acylase (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM152688 (1-Propylboronic acid (C3-B(OH)2)) Show SMILES CCCB(O)O Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	4.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
The University of Texas					Assay Description Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...				Biochemistry 53: 6679-86 (2014) Article DOI: 10.1021/bi501086s BindingDB Entry DOI: 10.7270/Q2M907DK
The University of Texas					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50289509 (amino(prop-2-ynylamino)methaniminium) Show SMILES NC(=[NH2+])NCC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition against neuronal nitric oxide synthase (nNOS) from bovine brain was determined				Bioorg Med Chem Lett 7: 1449-1454 (1997) Article DOI: 10.1016/S0960-894X(97)00241-2 BindingDB Entry DOI: 10.7270/Q2XP75FF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metallo-beta-lactamase VIM-2 (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM50240870 (CHEMBL4068259) Show SMILES Nc1cccc(c1)-c1cc(nc(c1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 60: 7267-7283 (2017) Article DOI: 10.1021/acs.jmedchem.7b00407 BindingDB Entry DOI: 10.7270/Q2P27185
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM50240870 (CHEMBL4068259) Show SMILES Nc1cccc(c1)-c1cc(nc(c1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description Inhibition of Serratia marcescens IMP1 expressed in Escherichia coli BL21(DE3) using chromacef as substrate preincubated for 10 mins followed by subs...				J Med Chem 60: 7267-7283 (2017) Article DOI: 10.1021/acs.jmedchem.7b00407 BindingDB Entry DOI: 10.7270/Q2P27185
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Metallo-beta-lactamase VIM-2 (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM26116 (CHEMBL284104 \| Dipicolinate \| pyridine carboxylate...) Show SMILES OC(=O)c1cccc(n1)C(O)=O Show InChI	PDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa VIM2 expressed in Escherichia coli BL21(DE3) using chromacef as substrate preincubated for 10 mins followed by s...				J Med Chem 60: 7267-7283 (2017) Article DOI: 10.1021/acs.jmedchem.7b00407 BindingDB Entry DOI: 10.7270/Q2P27185
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM26116 (CHEMBL284104 \| Dipicolinate \| pyridine carboxylate...) Show SMILES OC(=O)c1cccc(n1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California at San Diego Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 60: 7267-7283 (2017) Article DOI: 10.1021/acs.jmedchem.7b00407 BindingDB Entry DOI: 10.7270/Q2P27185
University of California at San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50242405 ((2S)-2-amino-4-sulfanylbutanoic acid \| CHEMBL46966...) Show SMILES N[C@@H](CCS)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description Inhibition of human recombinant DDAH1				J Biol Chem 282: 34684-92 (2007) Article DOI: 10.1074/jbc.M707231200 BindingDB Entry DOI: 10.7270/Q2F47NZ3
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50404858 (CHEMBL351569) Show SMILES CCc1nc2ccccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ...				Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50421231 (CHEMBL2087646) Show SMILES NCCSc1nc2ccccc2o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ...				Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM50138983 ((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...) Show SMILES CSC(N)=NCCC[C@H](N)C(O)=O \|r,w:4.4\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92901 (ADMA, 3) Show SMILES CN(C)C(N)=NCCC[C@H](N)C(O)=O \|r,w:5.5\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM92900 (CHEMBL1835117 \| L-Arginine, 2 \| NMMA, 2) Show SMILES CN=C(N)NCCC[C@H](N)C(O)=O \|r,w:1.0\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas					Assay Description Inhibition assay using DDAH-1 and nNOS.				Biochemistry 48: 8624-35 (2009) Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P
The University of Texas					More data for this Ligand-Target Pair