| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM152724 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SpeB and Papain Kinetic Assay |
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| pH | 7.4±n/a |
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| Ki | 4.5e+4± 2e+3 nM |
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| IC50 | 7.7e+4± 1e+3 nM |
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| Comments | extracted |
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| Citation |  Wang, AY; González-Páez, GE; Wolan, DW Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor. Biochemistry54:4365-73 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM152724 |
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| n/a |
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| Name | BDBM152724 |
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| Synonyms: | 2477 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H10N2O2 |
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| Mol. Mass. | 190.1986 |
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| SMILES | O=C(NCC#N)OCc1ccccc1 |
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| Structure | 
|
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