| Reaction Details |
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 | Report a problem with these data |
| Target | Aurora kinase B |
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| Ligand | BDBM50242173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Aurora B Kinase Assay |
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| IC50 | 1.219e+4±n/a nM |
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| Citation |  Jung, Y; Shin, SY; Yong, Y; Jung, H; Ahn, S; Lee, YH; Lim, Y Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships. Chem Biol Drug Des85:574-85 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aurora kinase B |
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| Name: | Aurora kinase B |
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| Synonyms: | AIK2 | AIM-1 | AIM1 | AIRK2 | ARK2 | AURKB | AURKB_HUMAN | Aurora B kinase (aurB) | Aurora B-INCENP | Aurora kinase 2 | Aurora kinase B (AURKB) | Aurora-related kinase 2 | STK-1 | STK1 | STK12 | STK5 | Serine/threonine-protein kinase aurora B |
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| Type: | Protein |
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| Mol. Mass.: | 39327.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96GD4 |
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| Residue: | 344 |
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| Sequence: | MAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMEN
SSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEH
QLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATI
MEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYL
PPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGA
QDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA
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| BDBM50242173 |
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| n/a |
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| Name | BDBM50242173 |
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| Synonyms: | (2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yloxy)-3,4,5-trihydroxy-tetrahydro-2H-pyran-2-carboxylic acid | Baicali | Baicalin (9) | CHEMBL485818 | baicalin |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18O11 |
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| Mol. Mass. | 446.361 |
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| SMILES | O[C@H]1[C@H](Oc2cc3oc(cc(=O)c3c(O)c2O)-c2ccccc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O |r| |
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| Structure | 
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