| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen synthase kinase-3 beta |
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| Ligand | BDBM155167 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 6.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 19.1±n/a nM |
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| Comments | extracted |
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| Citation |  Nakayama, K; Sakai, D; Watanabe, K; Kohara, T; Aritomo, K Pyrimidone derivatives US Patent US9006232 Publication Date 4/14/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Glycogen synthase kinase-3 beta |
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| Name: | Glycogen synthase kinase-3 beta |
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| Synonyms: | Glycogen synthase kinase-3 beta (GSK3beta) | Tau protein kinase 1 (TPK1) |
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| Type: | Protein |
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| Mol. Mass.: | 46641.23 |
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| Organism: | Bos taurus (cattle) |
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| Description: | A0A059UE90 |
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| Residue: | 419 |
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| Sequence: | MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF
NFTTQELSSNPPLATILIPPHARIQAAASTPSNTTAASDANAGDRGQTNNAASASASDS
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| BDBM155167 |
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| n/a |
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| Name | BDBM155167 |
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| Synonyms: | US9006232, 1.201 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H39N7O4 |
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| Mol. Mass. | 561.6752 |
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| SMILES | Cn1c(OC2CCN(CC2)c2ccc(CN3CCN(CC3)C(=O)OC(C)(C)C)cc2)nc(cc1=O)-c1ccncn1 |
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| Structure | 
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