| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysosomal protective protein |
|---|
| Ligand | BDBM156743 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| pH | 5.5±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 94.4±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Ruf, S; Sadowski, T; Wirth, K; Schreuder, H; Buning, C Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals US Patent US9029559 Publication Date 5/12/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysosomal protective protein |
|---|
| Name: | Lysosomal protective protein |
|---|
| Synonyms: | CTSA | Cathepsin A | Cathepsin A (CTSA) | Lysosomal protective protein | PPGB | PPGB_HUMAN |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 54465.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P10619 |
|---|
| Residue: | 480 |
|---|
| Sequence: | MIRAAPPPLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYLKGSGSK
HLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLI
ANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYA
GIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHC
CSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQD
LGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWD
MCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKME
VQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY
|
|
|
|---|
| BDBM156743 |
|---|
| n/a |
|---|
| Name | BDBM156743 |
|---|
| Synonyms: | US9029559, 165 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H21FN2O3 |
|---|
| Mol. Mass. | 392.4228 |
|---|
| SMILES | Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cccc(n1)-c1cc(F)ccc1C |
|---|
| Structure | 
|
|---|
Search and Browse
