| Reaction Details |
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 | Report a problem with these data |
| Target | Ileal sodium/bile acid cotransporter |
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| Ligand | BDBM159835 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1±n/a nM |
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| Comments | extracted |
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| Citation |  Aquino, CJ; Collins, JL; Cowan, DJ; Wu, Y Chemical compounds US Patent US9040518 Publication Date 5/26/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Ileal sodium/bile acid cotransporter |
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| Name: | Ileal sodium/bile acid cotransporter |
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| Synonyms: | ASBT | Apical sodium-dependent bile acid transporter | IBAT | ISBT | Ileal Na(+)/bile acid cotransporter | Ileal bile acid transporter | Ileal bile acid transporter/bile acid cotransporter | Ileal sodium-dependent bile acid transporter | NTCP2 | NTCP2_HUMAN | SLC10A2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 37714.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | SLC10A2 |
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| Residue: | 348 |
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| Sequence: | MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLG
HIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVD
GDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGM
FVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSL
GFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAF
AAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
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| BDBM159835 |
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| n/a |
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| Name | BDBM159835 |
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| Synonyms: | US9040518, 68 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H41N3O6S |
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| Mol. Mass. | 559.717 |
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| SMILES | CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNC(CC(O)=O)CC(O)=O)c(cc2[C@H](N1)c1ccccc1)N(C)C |r| |
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| Structure | 
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