Reaction Details | |||
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Target | D(1A) dopamine receptor | ||
Ligand | BDBM160871 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Competition Binding Assay | ||
Ki | 5.41±n/a nM | ||
Citation | Brodney, MA; Davoren, JE; Dounay, AB; Efremov, IV; Gray, DL; Green, ME; Henderson, JL; Lee, C; Mente, SR; O'Neil, SV; Rogers, BN; Zhang, L Heteroaromatic compounds and their use as dopamine D1 ligands US Patent US9107923 Publication Date 8/18/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
D(1A) dopamine receptor | |||
Name: | D(1A) dopamine receptor | ||
Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | ||
Type: | Enzyme | ||
Mol. Mass.: | 49303.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P21728 | ||
Residue: | 446 | ||
Sequence: |
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BDBM160871 | |||
n/a | |||
Name | BDBM160871 | ||
Synonyms: | US10093655, Example 41 | US11014909, Example 41 | US9107923, 41 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H18ClN3O2 | ||
Mol. Mass. | 355.818 | ||
SMILES | Cc1ccnc(Oc2ccc(c(C)c2)-c2c(C)n[nH]c(=O)c2C)c1Cl |(-5.33,-5.77,;-4,-5,;-2.67,-5.78,;-1.33,-5,;-1.33,-3.47,;-2.67,-2.69,;-2.67,-1.15,;-1.33,-.38,;,-1.15,;1.33,-.38,;1.33,1.15,;,1.93,;,3.47,;-1.33,1.15,;2.67,1.93,;4,1.15,;4,-.38,;5.33,1.93,;5.33,3.47,;4,4.23,;4,5.78,;2.67,3.47,;1.33,4.23,;-4,-3.47,;-5.33,-2.69,)| | ||
Structure |