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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Catenin beta-1/Protein Wnt-3a | ||
| Ligand | BDBM143712 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Luciferase Assay | ||
| IC50 | <300±n/a nM | ||
| Citation |  Moriyama, H; Sawa, M; Uno, Y; Kashimoto, S; Yamada, T Quinazoline derivative US Patent US9682961 Publication Date 6/20/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Catenin beta-1/Protein Wnt-3a | |||
| Name: | Catenin beta-1/Protein Wnt-3a | ||
| Synonyms: | Wnt/beta-Catenin | ||
| Type: | Protein | ||
| Mol. Mass.: | n/a | ||
| Description: | n/a | ||
| Components: | This complex has 2 components. | ||
| Component 1 | |||
| Name: | Protein Wnt-3a | ||
| Synonyms: | WNT3A | WNT3A_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 39379.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1469237 | ||
| Residue: | 352 | ||
| Sequence: |
| ||
| Component 2 | |||
| Name: | Catenin beta-1 | ||
| Synonyms: | CTNB1_HUMAN | CTNNB | CTNNB1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 85484.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1504364 | ||
| Residue: | 781 | ||
| Sequence: |
| ||
| BDBM143712 | |||
| n/a | |||
| Name | BDBM143712 | ||
| Synonyms: | US9682961, 1 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H21N5O2 | ||
| Mol. Mass. | 375.4237 | ||
| SMILES | O[C@H]1CC[C@H](CC1)Oc1cccc2cnc(Nc3ccc4nc[nH]c4c3)nc12 |r,wU:4.7,1.0,(8.52,-4.99,;7.19,-4.22,;5.85,-4.99,;4.52,-4.22,;4.52,-2.68,;5.85,-1.91,;7.19,-2.68,;3.19,-1.91,;3.19,-.37,;4.52,.4,;4.52,1.94,;3.19,2.71,;1.85,1.94,;.52,2.71,;-.82,1.94,;-.82,.4,;-2.15,-.37,;-3.48,.4,;-3.48,1.94,;-4.82,2.71,;-6.15,1.94,;-7.61,2.41,;-8.52,1.17,;-7.61,-.08,;-6.15,.4,;-4.82,-.37,;.52,-.37,;1.85,.4,)| | ||
| Structure | 
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