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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Catenin beta-1/Protein Wnt-3a | ||
| Ligand | BDBM148360 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Luciferase Assay | ||
| IC50 | 650±n/a nM | ||
| Citation |  Moriyama, H; Sawa, M; Uno, Y; Kashimoto, S; Yamada, T Quinazoline derivative US Patent US9682961 Publication Date 6/20/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Catenin beta-1/Protein Wnt-3a | |||
| Name: | Catenin beta-1/Protein Wnt-3a | ||
| Synonyms: | Wnt/beta-Catenin | ||
| Type: | Protein | ||
| Mol. Mass.: | n/a | ||
| Description: | n/a | ||
| Components: | This complex has 2 components. | ||
| Component 1 | |||
| Name: | Protein Wnt-3a | ||
| Synonyms: | WNT3A | WNT3A_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 39379.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1469237 | ||
| Residue: | 352 | ||
| Sequence: |
| ||
| Component 2 | |||
| Name: | Catenin beta-1 | ||
| Synonyms: | CTNB1_HUMAN | CTNNB | CTNNB1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 85484.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1504364 | ||
| Residue: | 781 | ||
| Sequence: |
| ||
| BDBM148360 | |||
| n/a | |||
| Name | BDBM148360 | ||
| Synonyms: | US9682961, 14 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H23N5O3 | ||
| Mol. Mass. | 405.4497 | ||
| SMILES | OCc1nc2cc(Nc3ncc4cccc(O[C@@H]5CC[C@H](O)CC5)c4n3)ccc2[nH]1 |r,wU:17.16,20.20,(-9.68,.98,;-8.91,2.31,;-7.37,2.31,;-6.46,1.06,;-5,1.54,;-3.66,.77,;-2.33,1.54,;-.99,.77,;.34,1.54,;.34,3.08,;1.67,3.85,;3.01,3.08,;4.34,3.85,;5.67,3.08,;5.67,1.54,;4.34,.77,;4.34,-.77,;5.67,-1.54,;5.67,-3.08,;7.01,-3.85,;8.34,-3.08,;9.68,-3.85,;8.34,-1.54,;7.01,-.77,;3.01,1.54,;1.67,.77,;-2.33,3.08,;-3.66,3.85,;-5,3.08,;-6.46,3.56,)| | ||
| Structure | 
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