| Reaction Details |
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 | Report a problem with these data |
| Target | Protein mono-ADP-ribosyltransferase PARP3 [R100H] |
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| Ligand | BDBM167420 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Displacement Assay |
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| Kd | 50±n/a nM |
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| Citation |  Papeo, GM; Borghi, D; Caruso, M; Posteri, H; Krasavin, MY 3-Oxo-2,3-dihydro-1H-indazole-4-carboxamide derivatives as PARP-1 inhibitors US Patent US9073893 Publication Date 7/7/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein mono-ADP-ribosyltransferase PARP3 [R100H] |
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| Name: | Protein mono-ADP-ribosyltransferase PARP3 [R100H] |
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| Synonyms: | (ARTD3 or PARP3) | ADP-ribosyltransferase diphtheria toxin-like 3 | ADPRT3 | ADPRTL3 | Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3) | PARP3 | PARP3_HUMAN | Poly [ADP-ribose] polymerase 3 | Poly [ADP-ribose] polymerase 3 (PARP-3) | Poly(ADP-ribose) polymerase-3 (ARTD3/PARP3) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60071.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y6F1[R100H] |
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| Residue: | 533 |
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| Sequence: | MAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGT
QVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNHWGRVGEVGQSKINHFTRLED
AKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRV
QPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEAL
KGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQA
VSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWK
VNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENS
KSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPT
QDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
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| BDBM167420 |
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| n/a |
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| Name | BDBM167420 |
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| Synonyms: | US9073893, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15FN4O2 |
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| Mol. Mass. | 278.2822 |
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| SMILES | NC(=O)c1cc(F)cc2[nH]n(C3CCNCC3)c(=O)c12 |
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| Structure | 
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