| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM173467 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Dose-Displacement Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 277.15±n/a K |
|---|
| Ki | 0.26±0.03 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Kyle, DJ Quarternized buprenorphine analogs US Patent US9096606 Publication Date 8/4/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42648.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41145 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
|
|
|---|
| BDBM173467 |
|---|
| n/a |
|---|
| Name | BDBM173467 |
|---|
| Synonyms: | US9096606, 4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H39FNO4 |
|---|
| Mol. Mass. | 520.6548 |
|---|
| SMILES | CO[C@]12CC[C@@]3(C[C@@H]1COCc1ccc(F)cc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CC[N]1(C)CC1CC1)c45 |r,TLB:8:7:28.27:3.4| |
|---|
| Structure | 
|
|---|
Search and Browse
