| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM173537 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | α-Glucosidase Inhibitory Activity |
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| IC50 | 2.057e+5± 9.6e+3 nM |
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| Citation |  Taha, M; Ismail, NH; Javaid, K; Imran, S; Anouar, el H; Wadood, A; Atia-Tul-Wahab, null; Ali, M; Khan, KM; Saad, SM; Rahim, F; Choudhary, MI Evaluation of 2-indolcarbohydrazones as potent a-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions. Bioorg Chem63:24-35 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM173537 |
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| n/a |
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| Name | BDBM173537 |
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| Synonyms: | (E)-N'-(4-hydroxybenzylidene)-1H-indole-2-carbohydrazide (9) |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N3O2 |
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| Mol. Mass. | 279.2933 |
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| SMILES | Oc1ccc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc1 |
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| Structure | 
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