| Reaction Details |
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 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
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| Ligand | BDBM173575 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | α-Glucosidase Assay |
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| pH | 6.8±n/a |
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| IC50 | 2.68e+4± 3e+2 nM |
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| Comments | extracted |
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| Citation |  Riaz, S; Khan, IU; Bajda, M; Ashraf, M; Qurat-Ul-Ain, null; Shaukat, A; Rehman, TU; Mutahir, S; Hussain, S; Mustafa, G; Yar, M Pyridine sulfonamide as a small key organic molecule for the potential treatment of type-II diabetes mellitus and Alzheimer's disease: In vitro studies against yeast a-glucosidase, acetylcholinesterase and butyrylcholinesterase. Bioorg Chem63:64-71 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oligo-1,6-glucosidase IMA1 |
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| Name: | Oligo-1,6-glucosidase IMA1 |
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| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
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| Type: | Protein |
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| Mol. Mass.: | 68577.59 |
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| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
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| Description: | n/a |
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| Residue: | 589 |
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| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
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| BDBM173575 |
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| n/a |
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| Name | BDBM173575 |
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| Synonyms: | N',N'',N'''-(pyridine-2,4,6-tricarbonyl)tris(4-bromobenzenesulfonohydrazide) (4b) |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20Br3N7O9S3 |
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| Mol. Mass. | 910.385 |
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| SMILES | Brc1ccc(cc1)S(=O)(=O)NNC(=O)c1cc(nc(c1)C(=O)NNS(=O)(=O)c1ccc(Br)cc1)C(=O)NNS(=O)(=O)c1ccc(Br)cc1 |
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| Structure | 
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