| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium-transporting ATPase alpha chain 1 |
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| Ligand | BDBM50155436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | High Throughput Screening Assay |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 65000±n/a nM |
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| Comments | extracted |
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| Citation |  Xie, Z; Shapiro, JI; Si, S; Zhang, Z Na/K-ATPase ligands, ouabain antagonists, assays and uses thereof US Patent US9114126 Publication Date 8/25/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium-transporting ATPase alpha chain 1 |
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| Name: | Potassium-transporting ATPase alpha chain 1 |
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| Synonyms: | ATP4A | ATP4A_PIG | Gastric H(+)/K(+) ATPase subunit alpha | H+/K+-ATPase | Na/K-ATPase | Potassium-transporting ATPase | Potassium-transporting ATPase alpha chain 1 | Proton pump |
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| Type: | Enzyme |
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| Mol. Mass.: | 114279.23 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P19156 |
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| Residue: | 1034 |
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| Sequence: | MGKAENYELYQVELGPGPSGDMAAKMSKKKAGRGGGKRKEKLENMKKEMEINDHQLSVAE
LEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAI
CLIAFAIQASEGDLTTDDNLYLALALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQAT
VIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILQAQGRKVDNSSLTGESEPQTRSPE
CTHESPLETRNIAFFSTMCLEGTAQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEH
FVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKR
LASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHSADTTEDQSGQT
FDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGY
RERFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHVLVMKGAPERVLERCSSILIKGQELPL
DEQWREAFQTAYLSLGGLGERVLGFCQLYLSEKDYPPGYAFDVEAMNFPTSGLSFAGLVS
MIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRV
PVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGA
IVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFD
NLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESD
IMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRPQW
ENHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEMCQIADVLIRKTRRLSAFQQGFF
RNRILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPMPFGLLIFVYDEIRKLGV
RCCPGSWWDQELYY
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| BDBM50155436 |
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| n/a |
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| Name | BDBM50155436 |
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| Synonyms: | 1,3,5-Trihydroxy-xanthen-9-one | CHEMBL365234 | US9114126, MB3 | Xanthen-9-one, 1.4 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H8O5 |
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| Mol. Mass. | 244.1996 |
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| SMILES | Oc1cc(O)c2c(c1)oc1c(O)cccc1c2=O |
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| Structure | 
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