| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50310925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorometric Imaging Plate Reader (FLIPR) Asssay |
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| IC50 | 19.4±n/a nM |
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| Citation |  Jordan, A; Bedford, S; Burkhard, K; Yule, I; Poullennec, K Thienopyrimidine compounds US Patent US9120807 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50310925 |
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| n/a |
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| Name | BDBM50310925 |
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| Synonyms: | CHEMBL1081160 | US9120807, 7 | {6-dimethylamino-2-[(pyridine-3-ylmethyl)-amino]-thieno[3,2-d]pyrimidin-4-yl}-thiophen-2-yl-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17N5OS2 |
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| Mol. Mass. | 395.501 |
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| SMILES | CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 |
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| Structure | 
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