| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50310922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorometric Imaging Plate Reader (FLIPR) Asssay |
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| IC50 | 7.1±n/a nM |
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| Citation |  Jordan, A; Bedford, S; Burkhard, K; Yule, I; Poullennec, K Thienopyrimidine compounds US Patent US9120807 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50310922 |
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| n/a |
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| Name | BDBM50310922 |
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| Synonyms: | CHEMBL1080241 | US9120807, 9 | {6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2-d]pyrimidin-4-yl}-thiophen-2-yl-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N5OS2 |
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| Mol. Mass. | 367.448 |
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| SMILES | Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 |
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| Structure | 
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