| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesteryl ester transfer protein |
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| Ligand | BDBM179503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay (SPA) |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 169±n/a nM |
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| Comments | extracted |
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| Citation |  Anand, R; Colandrea, VJ; Reiter, M; Vachal, P; Zwicker, A; Wilson, JE; Zhang, F; Zhao, K Substituted benzopiperazines as CETP inhibitors US Patent US9126976 Publication Date 9/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesteryl ester transfer protein |
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| Name: | Cholesteryl ester transfer protein |
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| Synonyms: | CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I |
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| Type: | Enzyme |
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| Mol. Mass.: | 54751.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11597 |
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| Residue: | 493 |
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| Sequence: | MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
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| BDBM179503 |
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| n/a |
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| Name | BDBM179503 |
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| Synonyms: | US9126976, 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20Cl2F6N2O |
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| Mol. Mass. | 549.336 |
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| SMILES | O[C@H](CN1[C@@H](CN(Cc2cccc(Cl)c2Cl)c2ccccc12)c1cccc(c1)C(F)(F)F)C(F)(F)F |r| |
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| Structure | 
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