| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
|---|
| Ligand | BDBM179781 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Assay for α-Glucosidase Inhibitory Activity |
|---|
| IC50 | 5.30e+3± 1.0e+2 nM |
|---|
| Citation |  Taha, M; Ismail, NH; Imran, S; Mohamad, MH; Wadood, A; Rahim, F; Saad, SM; Rehman, AU; Khan, KM Synthesis, a-glucosidase inhibitory, cytotoxicity and docking studies of 2-aryl-7-methylbenzimidazoles. Bioorg Chem65:100-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oligo-1,6-glucosidase IMA1 |
|---|
| Name: | Oligo-1,6-glucosidase IMA1 |
|---|
| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68577.59 |
|---|
| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
|---|
| Description: | n/a |
|---|
| Residue: | 589 |
|---|
| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
|
|
|
|---|
| BDBM179781 |
|---|
| n/a |
|---|
| Name | BDBM179781 |
|---|
| Synonyms: | 2-(2'-Chlorophenyl)-7-methyl-1H-benzo[d]imidazole (25) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H11ClN2 |
|---|
| Mol. Mass. | 242.704 |
|---|
| SMILES | Cc1cccc2nc([nH]c12)-c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
