| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM180030 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Competitive Activity-Based Protein Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | >6250±n/a nM |
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| Comments | extracted |
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| Citation |  Cisar, JS; Grice, CA; Jones, TK; Niphakis, MJ; Chang, JW; Lum, KM; Cravatt, BF Carbamate compounds and of making and using same US Patent US9133148 Publication Date 9/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH1_MOUSE | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Hydrolase; single-pass membrane protein; homodimer |
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| Mol. Mass.: | 63227.28 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Mouse brain membranes were used in the assay. |
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| Residue: | 579 |
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| Sequence: | MVLSEVWTALSGLSGVCLACSLLSAAVVLRWTRSQTARGAVTRARQKQRAGLETMDKAVQ
RFRLQNPDLDSEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTD
CETQLSQAPRQGLLYGVPVSLKECFSYKGHASTLGLSLNEGVTSESDCVVVQVLKLQGAV
PFVHTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSAFCGICGLKPTGNRLSKSGLKSCVYGQTAVQLSVGPMARDVDSLALCMKALLCE
DLFRLDSTIPPLPFREEIYRSSRPLRVGYYETDNYTMPTPAMRRAVMETKQSLEAAGHTL
VPFLPNNIPYALEVLSAGGLFSDGGCSFLQNFKGDFVDPCLGDLVLVLKLPRWFKKLLSF
LLKPLFPRLAAFLNSMCPRSAEKLWELQHEIEMYRQSVIAQWKAMNLDVVLTPMLGPALD
LNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMEHYKGYFGDMWDNILKKGMK
KGIGLPVAVQCVALPWQEELCLRFMREVERLMTPEKRPS
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| BDBM180030 |
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| n/a |
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| Name | BDBM180030 |
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| Synonyms: | US9133148, 9u |
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| Type | Small organic molecule |
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| Emp. Form. | C20H25F6N3O2 |
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| Mol. Mass. | 453.4218 |
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| SMILES | Cc1cc(ccc1CN1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)N1CCCC1 |
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| Structure | 
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