| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 3A4 |
|---|
| Ligand | BDBM50176808 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | n/a |
|---|
| IC50 | <100±n/a nM |
|---|
| Citation |  Bareja, SP; Jones, SD; Oblong, JE; Mills, KJ; Bierman, JC Cosmetic compositions containing substituted azole and methods for improving the appearance of aging skin US Patent US9138393 Publication Date 9/22/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 3A4 |
|---|
| Name: | Cytochrome P450 3A4 |
|---|
| Synonyms: | Albendazole monooxygenase | Albendazole sulfoxidase | CP3A4_HUMAN | CYP3A3 | CYP3A4 | CYPIIIA3 | CYPIIIA4 | Cytochrome P450 3A3 | Cytochrome P450 3A4 (CYP3A4) | Cytochrome P450 HLp | Nifedipine oxidase | Quinine 3-monooxygenase | Taurochenodeoxycholate 6-alpha-hydroxylase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 57349.57 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 503 |
|---|
| Sequence: | MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMF
DMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYS
MDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICV
FPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSI
IFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVV
NETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLG
GLLQPEKPVVLKVESRDGTVSGA
|
|
|
|---|
| BDBM50176808 |
|---|
| n/a |
|---|
| Name | BDBM50176808 |
|---|
| Synonyms: | 5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benzoimidazole | 6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole | CHEMBL389433 | US9138393, Liarizole hydrochloride | US9144538, Liarizole hydrochloride | liarozole |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H13ClN4 |
|---|
| Mol. Mass. | 308.765 |
|---|
| SMILES | Clc1cccc(c1)C(c1ccc2nc[nH]c2c1)n1ccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
