Reaction Details | |||
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Target | Cell division cycle 7-related protein kinase | ||
Ligand | BDBM185848 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
pH | 7.5±n/a | ||
Ki | 2.25±n/a nM | ||
Comments | extracted | ||
Citation | Akritopoulou-Zanze, I; Wakefield, BD; Mack, H; Turner, SC; Gasiecki, AF; Gracias, VJ; Sarris, KA; Kalvin, DM; Michmerhuizen, MJ; Shuai, Q; Patel, JR; Bakker, MH; Teusch, N; Johnson, EF; Kovar, PJ; Djuric, SW; Long, AJ; Vasudevan, A; George, DM; Wang, L; Li, B; Moore, NS; Hobson, AD; Woods, KW; Miyashiro, JM; Swann, Jr., SL; Penning, TD 5-substituted indazoles as kinase inhibitors US Patent US9163007 Publication Date 10/20/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cell division cycle 7-related protein kinase | |||
Name: | Cell division cycle 7-related protein kinase | ||
Synonyms: | CDC7 | CDC7-related kinase | CDC7L1 | CDC7_HUMAN | Cell division cycle 7-related protein kinase (CDC7) | HsCdc7 | huCdc7 | ||
Type: | Protein | ||
Mol. Mass.: | 63908.16 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O00311 | ||
Residue: | 574 | ||
Sequence: |
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BDBM185848 | |||
n/a | |||
Name | BDBM185848 | ||
Synonyms: | US9163007, 162 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H21N5 | ||
Mol. Mass. | 379.457 | ||
SMILES | Cc1n[nH]c2ccc(cc12)-c1nnn(Cc2ccccc2)c1-c1ccccc1C |(1.65,-4.01,;2.13,-2.55,;1.22,-1.3,;2.13,-.06,;3.59,-.53,;4.92,.24,;6.26,-.53,;6.26,-2.07,;4.92,-2.84,;3.59,-2.07,;7.59,-2.84,;7.75,-4.37,;9.26,-4.69,;10.03,-3.36,;11.56,-3.2,;12.47,-4.45,;14,-4.28,;14.9,-5.53,;14.28,-6.94,;12.74,-7.1,;11.84,-5.85,;9,-2.22,;9.32,-.71,;8.17,.32,;8.49,1.83,;9.96,2.3,;11.1,1.27,;10.78,-.23,;11.93,-1.26,)| | ||
Structure |